Effect of xanthine oxidase-catalyzed reactive oxygen species generation on secretagogue-evoked calcium mobilization in mouse pancreatic acinar cells††Abbreviations: ACh, acetylcholine; Ca2+, calcium; [Ca2+]i, intracellular free calcium concentration; CCK-8, cholecystokinin octapeptide; DAG, diacylglycerol; IP3, inositol 1,4,5-trisphosphate; PIP2, phosphatidyl-inositol 4,5-bisphosphate; PLC, phospholipase C; ROS, reactive oxygen species; SERCA, sarco/endoplasmic reticulum Ca2+ ATPase; TPS, thapsigargin; and XOD, xanthine oxidase. | Publicación